Amyloid imaging with carbon 11-labeled Pittsburgh compound B for traumatic brain injury.
Identifieur interne : 000284 ( France/Analysis ); précédent : 000283; suivant : 000285Amyloid imaging with carbon 11-labeled Pittsburgh compound B for traumatic brain injury.
Auteurs : Young T. Hong [Royaume-Uni] ; Tonny Veenith [Royaume-Uni] ; Deborah Dewar [Royaume-Uni] ; Joanne G. Outtrim [Royaume-Uni] ; Vaithianadan Mani [Royaume-Uni] ; Claire Williams [Royaume-Uni] ; Sally Pimlott [Royaume-Uni] ; Peter J A. Hutchinson [Royaume-Uni] ; Adriana Tavares [Royaume-Uni] ; Roberto Canales [Royaume-Uni] ; Chester A. Mathis [États-Unis] ; William E. Klunk [États-Unis] ; Franklin I. Aigbirhio [Royaume-Uni] ; Jonathan P. Coles [Royaume-Uni] ; Jean-Claude Baron [France] ; John D. Pickard [Royaume-Uni] ; Tim D. Fryer [Royaume-Uni] ; William Stewart [Royaume-Uni] ; David K. Menon [Royaume-Uni]Source :
- JAMA neurology [ 2168-6157 ] ; 2014.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Dérivés de l'aniline, Encéphale (anatomopathologie), Encéphale (imagerie diagnostique), Encéphale (métabolisme), Facteurs temps, Femelle, Humains, Jeune adulte, Lésions encéphaliques (anatomopathologie), Lésions encéphaliques (imagerie diagnostique), Lésions encéphaliques (métabolisme), Mâle, Peptides bêta-amyloïdes (métabolisme), Radio-isotopes du carbone, Sujet âgé, Thiazoles, Tomographie par émission de positons (), Tritium, Études de cohortes.
- MESH :
- anatomopathologie : Encéphale, Lésions encéphaliques.
- imagerie diagnostique : Encéphale, Lésions encéphaliques.
- métabolisme : Encéphale, Lésions encéphaliques, Peptides bêta-amyloïdes.
- Adulte, Adulte d'âge moyen, Dérivés de l'aniline, Facteurs temps, Femelle, Humains, Jeune adulte, Mâle, Radio-isotopes du carbone, Sujet âgé, Thiazoles, Tomographie par émission de positons, Tritium, Études de cohortes.
English descriptors
- KwdEn :
- Adult, Aged, Amyloid beta-Peptides (metabolism), Aniline Compounds, Brain (diagnostic imaging), Brain (metabolism), Brain (pathology), Brain Injuries (diagnostic imaging), Brain Injuries (metabolism), Brain Injuries (pathology), Carbon Radioisotopes, Cohort Studies, Female, Humans, Male, Middle Aged, Positron-Emission Tomography (methods), Thiazoles, Time Factors, Tritium, Young Adult.
- MESH :
- chemical , metabolism : Amyloid beta-Peptides.
- diagnostic imaging : Brain, Brain Injuries.
- metabolism : Brain, Brain Injuries.
- methods : Positron-Emission Tomography.
- pathology : Brain, Brain Injuries.
- Adult, Aged, Aniline Compounds, Carbon Radioisotopes, Cohort Studies, Female, Humans, Male, Middle Aged, Thiazoles, Time Factors, Tritium, Young Adult.
Abstract
To image amyloid deposition in patients with traumatic brain injury (TBI) using carbon 11-labeled Pittsburgh Compound B ([11C]PiB) positron emission tomography (PET) and to validate these findings using tritium-labeled PiB ([3H]PiB) autoradiography and immunocytochemistry in autopsy-acquired tissue.
DOI: 10.1001/jamaneurol.2013.4847
PubMed: 24217171
Affiliations:
- France, Royaume-Uni, États-Unis
- Angleterre, Pennsylvanie, Écosse, Île-de-France
- Cambridge, Paris
- Université de Cambridge
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pubmed:24217171Le document en format XML
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Hong</name><affiliation wicri:level="2"><nlm:affiliation>Wolfson Brain Imaging Centre, University of Cambridge, Cambridge, England5Department of Clinical Neurosciences, University of Cambridge, Cambridge, England.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Wolfson Brain Imaging Centre, University of Cambridge, Cambridge, England5Department of Clinical Neurosciences, University of Cambridge, Cambridge</wicri:cityArea></affiliation></author><author><name sortKey="Veenith, Tonny" sort="Veenith, Tonny" uniqKey="Veenith T" first="Tonny" last="Veenith">Tonny Veenith</name><affiliation wicri:level="2"><nlm:affiliation>Division of Anaesthesia, University of Cambridge, Addenbrooke's Hospital, Cambridge, England.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Division of Anaesthesia, University of Cambridge, Addenbrooke's Hospital, Cambridge</wicri:cityArea></affiliation></author><author><name sortKey="Dewar, Deborah" sort="Dewar, Deborah" uniqKey="Dewar D" first="Deborah" last="Dewar">Deborah Dewar</name><affiliation wicri:level="2"><nlm:affiliation>Institute of Neuroscience and Psychology, University of Glasgow, Scotland.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>Institute of Neuroscience and Psychology, University of Glasgow</wicri:cityArea></affiliation></author><author><name sortKey="Outtrim, Joanne G" sort="Outtrim, Joanne G" uniqKey="Outtrim J" first="Joanne G" last="Outtrim">Joanne G. Outtrim</name><affiliation wicri:level="2"><nlm:affiliation>Division of Anaesthesia, University of Cambridge, Addenbrooke's Hospital, Cambridge, England.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Division of Anaesthesia, University of Cambridge, Addenbrooke's Hospital, Cambridge</wicri:cityArea></affiliation></author><author><name sortKey="Mani, Vaithianadan" sort="Mani, Vaithianadan" uniqKey="Mani V" first="Vaithianadan" last="Mani">Vaithianadan Mani</name><affiliation wicri:level="2"><nlm:affiliation>Division of Anaesthesia, University of Cambridge, Addenbrooke's Hospital, Cambridge, England.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Division of Anaesthesia, University of Cambridge, Addenbrooke's Hospital, Cambridge</wicri:cityArea></affiliation></author><author><name sortKey="Williams, Claire" sort="Williams, Claire" uniqKey="Williams C" first="Claire" last="Williams">Claire Williams</name><affiliation wicri:level="2"><nlm:affiliation>Division of Anaesthesia, University of Cambridge, Addenbrooke's Hospital, Cambridge, England.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Division of Anaesthesia, University of Cambridge, Addenbrooke's Hospital, Cambridge</wicri:cityArea></affiliation></author><author><name sortKey="Pimlott, Sally" sort="Pimlott, Sally" uniqKey="Pimlott S" first="Sally" last="Pimlott">Sally Pimlott</name><affiliation wicri:level="2"><nlm:affiliation>University of Glasgow and Southern General Hospital, Glasgow, Scotland.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>University of Glasgow and Southern General Hospital, Glasgow</wicri:cityArea></affiliation></author><author><name sortKey="Hutchinson, Peter J A" sort="Hutchinson, Peter J A" uniqKey="Hutchinson P" first="Peter J A" last="Hutchinson">Peter J A. Hutchinson</name><affiliation wicri:level="2"><nlm:affiliation>Department of Clinical Neurosciences, University of Cambridge, Cambridge, England.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Department of Clinical Neurosciences, University of Cambridge, Cambridge</wicri:cityArea></affiliation></author><author><name sortKey="Tavares, Adriana" sort="Tavares, Adriana" uniqKey="Tavares A" first="Adriana" last="Tavares">Adriana Tavares</name><affiliation wicri:level="2"><nlm:affiliation>Institute of Neuroscience and Psychology, University of Glasgow, Scotland.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>Institute of Neuroscience and Psychology, University of Glasgow</wicri:cityArea></affiliation></author><author><name sortKey="Canales, Roberto" sort="Canales, Roberto" uniqKey="Canales R" first="Roberto" last="Canales">Roberto Canales</name><affiliation wicri:level="2"><nlm:affiliation>Wolfson Brain Imaging Centre, University of Cambridge, Cambridge, England5Department of Clinical Neurosciences, University of Cambridge, Cambridge, England.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Wolfson Brain Imaging Centre, University of Cambridge, Cambridge, England5Department of Clinical Neurosciences, University of Cambridge, Cambridge</wicri:cityArea></affiliation></author><author><name sortKey="Mathis, Chester A" sort="Mathis, Chester A" uniqKey="Mathis C" first="Chester A" last="Mathis">Chester A. Mathis</name><affiliation wicri:level="2"><nlm:affiliation>Departments of Radiology and Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName><wicri:cityArea>Departments of Radiology and Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh</wicri:cityArea></affiliation></author><author><name sortKey="Klunk, William E" sort="Klunk, William E" uniqKey="Klunk W" first="William E" last="Klunk">William E. Klunk</name><affiliation wicri:level="2"><nlm:affiliation>Departments of Psychiatry and Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Pennsylvanie</region></placeName><wicri:cityArea>Departments of Psychiatry and Neurology, University of Pittsburgh School of Medicine, Pittsburgh</wicri:cityArea></affiliation></author><author><name sortKey="Aigbirhio, Franklin I" sort="Aigbirhio, Franklin I" uniqKey="Aigbirhio F" first="Franklin I" last="Aigbirhio">Franklin I. Aigbirhio</name><affiliation wicri:level="2"><nlm:affiliation>Wolfson Brain Imaging Centre, University of Cambridge, Cambridge, England5Department of Clinical Neurosciences, University of Cambridge, Cambridge, England.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Wolfson Brain Imaging Centre, University of Cambridge, Cambridge, England5Department of Clinical Neurosciences, University of Cambridge, Cambridge</wicri:cityArea></affiliation></author><author><name sortKey="Coles, Jonathan P" sort="Coles, Jonathan P" uniqKey="Coles J" first="Jonathan P" last="Coles">Jonathan P. Coles</name><affiliation wicri:level="2"><nlm:affiliation>Division of Anaesthesia, University of Cambridge, Addenbrooke's Hospital, Cambridge, England.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Division of Anaesthesia, University of Cambridge, Addenbrooke's Hospital, Cambridge</wicri:cityArea></affiliation></author><author><name sortKey="Baron, Jean Claude" sort="Baron, Jean Claude" uniqKey="Baron J" first="Jean-Claude" last="Baron">Jean-Claude Baron</name><affiliation wicri:level="4"><nlm:affiliation>Wolfson Brain Imaging Centre, University of Cambridge, Cambridge, England5Department of Clinical Neurosciences, University of Cambridge, Cambridge, England8INSERM U894, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Wolfson Brain Imaging Centre, University of Cambridge, Cambridge, England5Department of Clinical Neurosciences, University of Cambridge, Cambridge, England8INSERM U894, Université Paris Descartes, Sorbonne Paris Cité, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement><settlement type="city">Cambridge</settlement></placeName><orgName type="university">Université de Cambridge</orgName></affiliation></author><author><name sortKey="Pickard, John D" sort="Pickard, John D" uniqKey="Pickard J" first="John D" last="Pickard">John D. Pickard</name><affiliation wicri:level="2"><nlm:affiliation>Wolfson Brain Imaging Centre, University of Cambridge, Cambridge, England5Department of Clinical Neurosciences, University of Cambridge, Cambridge, England.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Wolfson Brain Imaging Centre, University of Cambridge, Cambridge, England5Department of Clinical Neurosciences, University of Cambridge, Cambridge</wicri:cityArea></affiliation></author><author><name sortKey="Fryer, Tim D" sort="Fryer, Tim D" uniqKey="Fryer T" first="Tim D" last="Fryer">Tim D. Fryer</name><affiliation wicri:level="2"><nlm:affiliation>Wolfson Brain Imaging Centre, University of Cambridge, Cambridge, England5Department of Clinical Neurosciences, University of Cambridge, Cambridge, England.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Wolfson Brain Imaging Centre, University of Cambridge, Cambridge, England5Department of Clinical Neurosciences, University of Cambridge, Cambridge</wicri:cityArea></affiliation></author><author><name sortKey="Stewart, William" sort="Stewart, William" uniqKey="Stewart W" first="William" last="Stewart">William Stewart</name><affiliation wicri:level="2"><nlm:affiliation>University of Glasgow and Southern General Hospital, Glasgow, Scotland.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Écosse</region></placeName><wicri:cityArea>University of Glasgow and Southern General Hospital, Glasgow</wicri:cityArea></affiliation></author><author><name sortKey="Menon, David K" sort="Menon, David K" uniqKey="Menon D" first="David K" last="Menon">David K. Menon</name><affiliation wicri:level="2"><nlm:affiliation>Wolfson Brain Imaging Centre, University of Cambridge, Cambridge, England2Division of Anaesthesia, University of Cambridge, Addenbrooke's Hospital, Cambridge, England.</nlm:affiliation><country>Royaume-Uni</country><placeName><region type="country">Angleterre</region></placeName><wicri:cityArea>Wolfson Brain Imaging Centre, University of Cambridge, Cambridge, England2Division of Anaesthesia, University of Cambridge, Addenbrooke's Hospital, Cambridge</wicri:cityArea></affiliation></author></analytic><series><title level="j">JAMA neurology</title><idno type="eISSN">2168-6157</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Amyloid beta-Peptides (metabolism)</term><term>Aniline Compounds</term><term>Brain (diagnostic imaging)</term><term>Brain (metabolism)</term><term>Brain (pathology)</term><term>Brain Injuries (diagnostic imaging)</term><term>Brain Injuries (metabolism)</term><term>Brain Injuries (pathology)</term><term>Carbon Radioisotopes</term><term>Cohort Studies</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Positron-Emission Tomography (methods)</term><term>Thiazoles</term><term>Time Factors</term><term>Tritium</term><term>Young Adult</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Dérivés de l'aniline</term><term>Encéphale (anatomopathologie)</term><term>Encéphale (imagerie diagnostique)</term><term>Encéphale (métabolisme)</term><term>Facteurs temps</term><term>Femelle</term><term>Humains</term><term>Jeune adulte</term><term>Lésions encéphaliques (anatomopathologie)</term><term>Lésions encéphaliques (imagerie diagnostique)</term><term>Lésions encéphaliques (métabolisme)</term><term>Mâle</term><term>Peptides bêta-amyloïdes (métabolisme)</term><term>Radio-isotopes du carbone</term><term>Sujet âgé</term><term>Thiazoles</term><term>Tomographie par émission de positons ()</term><term>Tritium</term><term>Études de cohortes</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Amyloid beta-Peptides</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Encéphale</term><term>Lésions encéphaliques</term></keywords><keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Brain</term><term>Brain Injuries</term></keywords><keywords scheme="MESH" qualifier="imagerie diagnostique" xml:lang="fr"><term>Encéphale</term><term>Lésions encéphaliques</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Brain</term><term>Brain Injuries</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Positron-Emission Tomography</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Encéphale</term><term>Lésions encéphaliques</term><term>Peptides bêta-amyloïdes</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Brain</term><term>Brain Injuries</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aniline Compounds</term><term>Carbon Radioisotopes</term><term>Cohort Studies</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Thiazoles</term><term>Time Factors</term><term>Tritium</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Dérivés de l'aniline</term><term>Facteurs temps</term><term>Femelle</term><term>Humains</term><term>Jeune adulte</term><term>Mâle</term><term>Radio-isotopes du carbone</term><term>Sujet âgé</term><term>Thiazoles</term><term>Tomographie par émission de positons</term><term>Tritium</term><term>Études de cohortes</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To image amyloid deposition in patients with traumatic brain injury (TBI) using carbon 11-labeled Pittsburgh Compound B ([11C]PiB) positron emission tomography (PET) and to validate these findings using tritium-labeled PiB ([3H]PiB) autoradiography and immunocytochemistry in autopsy-acquired tissue.</div></front></TEI><affiliations><list><country><li>France</li><li>Royaume-Uni</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Pennsylvanie</li><li>Écosse</li><li>Île-de-France</li></region><settlement><li>Cambridge</li><li>Paris</li></settlement><orgName><li>Université de Cambridge</li></orgName></list><tree><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Hong, Young T" sort="Hong, Young T" uniqKey="Hong Y" first="Young T" last="Hong">Young T. Hong</name></region><name sortKey="Aigbirhio, Franklin I" sort="Aigbirhio, Franklin I" uniqKey="Aigbirhio F" first="Franklin I" last="Aigbirhio">Franklin I. Aigbirhio</name><name sortKey="Canales, Roberto" sort="Canales, Roberto" uniqKey="Canales R" first="Roberto" last="Canales">Roberto Canales</name><name sortKey="Coles, Jonathan P" sort="Coles, Jonathan P" uniqKey="Coles J" first="Jonathan P" last="Coles">Jonathan P. Coles</name><name sortKey="Dewar, Deborah" sort="Dewar, Deborah" uniqKey="Dewar D" first="Deborah" last="Dewar">Deborah Dewar</name><name sortKey="Fryer, Tim D" sort="Fryer, Tim D" uniqKey="Fryer T" first="Tim D" last="Fryer">Tim D. Fryer</name><name sortKey="Hutchinson, Peter J A" sort="Hutchinson, Peter J A" uniqKey="Hutchinson P" first="Peter J A" last="Hutchinson">Peter J A. Hutchinson</name><name sortKey="Mani, Vaithianadan" sort="Mani, Vaithianadan" uniqKey="Mani V" first="Vaithianadan" last="Mani">Vaithianadan Mani</name><name sortKey="Menon, David K" sort="Menon, David K" uniqKey="Menon D" first="David K" last="Menon">David K. Menon</name><name sortKey="Outtrim, Joanne G" sort="Outtrim, Joanne G" uniqKey="Outtrim J" first="Joanne G" last="Outtrim">Joanne G. Outtrim</name><name sortKey="Pickard, John D" sort="Pickard, John D" uniqKey="Pickard J" first="John D" last="Pickard">John D. Pickard</name><name sortKey="Pimlott, Sally" sort="Pimlott, Sally" uniqKey="Pimlott S" first="Sally" last="Pimlott">Sally Pimlott</name><name sortKey="Stewart, William" sort="Stewart, William" uniqKey="Stewart W" first="William" last="Stewart">William Stewart</name><name sortKey="Tavares, Adriana" sort="Tavares, Adriana" uniqKey="Tavares A" first="Adriana" last="Tavares">Adriana Tavares</name><name sortKey="Veenith, Tonny" sort="Veenith, Tonny" uniqKey="Veenith T" first="Tonny" last="Veenith">Tonny Veenith</name><name sortKey="Williams, Claire" sort="Williams, Claire" uniqKey="Williams C" first="Claire" last="Williams">Claire Williams</name></country><country name="États-Unis"><region name="Pennsylvanie"><name sortKey="Mathis, Chester A" sort="Mathis, Chester A" uniqKey="Mathis C" first="Chester A" last="Mathis">Chester A. Mathis</name></region><name sortKey="Klunk, William E" sort="Klunk, William E" uniqKey="Klunk W" first="William E" last="Klunk">William E. Klunk</name></country><country name="France"><region name="Île-de-France"><name sortKey="Baron, Jean Claude" sort="Baron, Jean Claude" uniqKey="Baron J" first="Jean-Claude" last="Baron">Jean-Claude Baron</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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